Designing polymeric particles for antigen delivery.

نویسندگان

  • Stefaan De Koker
  • Bart N Lambrecht
  • Monique A Willart
  • Yvette van Kooyk
  • Johan Grooten
  • Chris Vervaet
  • Jean Paul Remon
  • Bruno G De Geest
چکیده

By targeting dendritic cells, polymeric carriers in the nano to lower micron range constitute very interesting tools for antigen delivery. In this critical review, we review how new immunological insights can be exploited to design new carriers allowing one to tune immune responses and to further increase vaccine potency (137 references).

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Potential of polymeric particles as future vaccine delivery systems/adjuvants for parenteral and non-parenteral immunization against tuberculosis: A systematic review

Objective(s): Production of effective tuberculosis (TB) vaccine is necessity. However, the development of new subunit vaccines is faced with concerns about their weak immunogenicity. To overcome such problems, polymers-based vaccine delivery systems have been proposed to be used via various routes. The purpose of this study was to determine the potential of polymeric particles as future vaccine...

متن کامل

Nano-gels: A versatile nano -carrier platform for drug delivery systems: A mini review

Nowadays the application of nanotechnology in different biomedical fields such as drug delivery is increasing due to its unique advantages. With this in mind, it is widely believed that nanogels as the nanometer-sized networked polymeric particles have a considerable impact on drug delivery systems as biocompatible nanocarriers due to their unique characteristics such as high loading capacity, ...

متن کامل

Colloids: Applications and Remaining Challenges

Using of colloids and polymeric microparticles are gradually increasing. It is observed that the positive effects of particles stems in both traditional applications such as column pickings, coatings and paints to more recent technologies in diagnostics, drug delivery and optical devices are well documented. This review focuses on importance of colloids and covers their applications on three le...

متن کامل

Colloids: Applications and Remaining Challenges

Using of colloids and polymeric microparticles are gradually increasing. It is observed that the positive effects of particles stems in both traditional applications such as column pickings, coatings and paints to more recent technologies in diagnostics, drug delivery and optical devices are well documented. This review focuses on importance of colloids and covers their applications on three le...

متن کامل

Polymer Nanoparticles for Smart Drug Delivery

In the recent decades, polymers are widely used as biomaterials due to their favorable properties such as good biocompatibility, easy design and preparation, a variety of structures and interesting bio-mimetic character. Especially in the field of smart drug delivery, polymer played a significant role because it can deliver therapeutic agents directly into the intended site of action, with supe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Chemical Society reviews

دوره 40 1  شماره 

صفحات  -

تاریخ انتشار 2011